Tuesday, April 16, 2013

Selena Gomez Promises To 'Put On A Show' At MTV Movie Awards

Singer admits to pre-performance jitters on the red carpet Sunday, before taking the stage to perform 'Come & Get It.'
By Jocelyn Vena, with reporting by Josh Horowitz


Selena Gomez at the 2013 MTV Movie Awards
Photo: Kevin Mazur/ WireImage

Source: http://www.mtv.com/news/articles/1705633/selena-gomez-red-carpet-mtv-movie-awards-2013.jhtml

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Monday, April 15, 2013

As US talks up diplomacy, NKorea takes hard line

U.S. Secretary of Sate John Kerry, left, is greeted by Japanese Foreign Minister Fumio Kishida prior to their meeting at Foreign Ministry's Iikura Guesthouse in Tokyo Sunday, April 14, 2013. After meeting with top Chinese leaders in Beijing, Kerry traveled to Tokyo to discuss the continuing North Korea crisis with Japanese officials. (AP Photo/Shizuo Kambayashi)

U.S. Secretary of Sate John Kerry, left, is greeted by Japanese Foreign Minister Fumio Kishida prior to their meeting at Foreign Ministry's Iikura Guesthouse in Tokyo Sunday, April 14, 2013. After meeting with top Chinese leaders in Beijing, Kerry traveled to Tokyo to discuss the continuing North Korea crisis with Japanese officials. (AP Photo/Shizuo Kambayashi)

U.S. Secretary of State John Kerry speaks during a "Tomodachi" youth event at U.S. Embassy in Tokyo Sunday, April 14, 2013. "Tomodachi" seeks to inspire and empower the young people of Japan and America, giving them the experiences, skills, and confidence to achieve their dreams and contribute to a better world with scholarships. (AP Photo/Paul J. Richards, Pool)

U.S. Secretary of State John Kerry, center, salutes as he prepares to depart Capitol International Airport in Beijing for Tokyo Sunday, April 14, 2013. At left is Kerry Senior Staff member Glen Johnson. (AP Photo/Paul J. Richards, Pool)

U.S. Secretary of State John Kerry, center, tours the Zojoji Buddhist temple in Tokyo Sunday, April 14, 2013. The United States and Japan on Sunday offered new talks with North Korea to resolve the increasingly dangerous standoff over its nuclear and missile programs, but said the reclusive communist government first must lower tensions and honor previous agreements. (AP Photo/Paul J. Richards, Pool)

U.S. Secretary of Sate John Kerry, left, whispers to Japanese Foreign Minister Fumio Kishida after their joint press conference at Foreign Ministry's Iikura Guesthouse in Tokyo, Sunday, April 14, 2013. Kerry and Kishida said their countries are committed to new talks with North Korea if the reclusive communist government begins abiding by previous agreements on its nuclear program. (AP Photo/Shizuo Kambayashi)

(AP) ? The United States and Japan opened the door Sunday to new nuclear talks if North Korea lowered tensions and honored past agreements, even as the saber-rattling government rejected South Korea's latest offer of dialogue as a "crafty trick."

U.S. Secretary of State John Kerry told reporters in Tokyo that North Korea would find "ready partners" in the United States if it began abandoning its nuclear program.

Japan's foreign minister, Fumio Kishida, also demanded a resolution to a dispute concerning Japanese citizens abducted decades ago by North Korean officials.

The diplomats seemed to point the way for a possible revival of the six-nation talks that have been suspended for four years.

China long pushed has for the process to resume without conditions. But the U.S. and allies South Korea and Japan fear rewarding North Korea for its belligerence and endless repetition of a cycle of tensions and failed talks that have prolonged the crisis.

Kerry's message of openness to diplomacy was clear, however unlikely the chances appeared that North Korean leader Kim Jong Un's government would meet the American's conditions.

"I'm not going to be so stuck in the mud that an opportunity to actually get something done is flagrantly wasted because of a kind of predetermined stubbornness," he told U.S.-based journalists.

"You have to keep your mind open. But fundamentally, the concept is they're going to have to show some kind of good faith here so we're not going to around and around in the same-old, same-old," he said.

Tensions have run high on the Korean Peninsula for months, with North Korea testing a nuclear device and its intercontinental ballistic missile technology.

The reclusive communist state hasn't stopped there. It has issued almost daily threats that have included possible nuclear strikes against the United States. Analysts and foreign officials say that is still beyond the North Koreans' capability.

While many threats have been dismissed as bluster, U.S. and South Korean say they believe the North in the coming days may test a mid-range missile designed to reach as far as Guam, the U.S. territory in the Pacific where the Pentagon is deploying a land-based missile-defense system.

Japan is the last stop on a 10-day trip overseas for Kerry, who visited Seoul and Beijing as well in recent days.

In South Korea, he strongly warned North Korea not to launch a missile and he reaffirmed U.S. defense of its allies in the region. In China, he secured a public pledge from Beijing, the lone government with significant influence over North Korea, to rid the North of nuclear weapons.

Before returning to the United States, Kerry planned a speech Monday in Japan on the Obama administration's Asia policy.

So far, Republican lawmakers in the U.S. have largely backed the administration's efforts on North Korea.

U.S. Sen. Marco Rubio, R-Fla., told CBS' "Face the Nation" that he was encouraged by Kerry's China visit and that he hoped "we can get the Chinese to care more about this issue.

U.S. Sen. John McCain of Arizona suggested on CNN's "State of the Union" that the U.S. make a counter-threat by using missile interceptors to hit any North Korean missile that is test-fired.

At each stop on his trip, Kerry stressed that the United States wanted a peaceful resolution of the North Korea situation six decades after a cease-fire ended the Korean War.

But North Korea on Sunday served a reminder of the difficult task ahead. Its Committee for the Peaceful Reunification of Korea said the government had no intention of talking with Seoul unless the South abandons its confrontational posture, as the North called it.

Seoul had pressed North Korea to discuss restarting operations at a joint factory park on the border and President Park Geun-hye has stressed peace opportunities after taking power from her more hard-line predecessor, Lee Myung-bak. The presidency expressed regret with North Korea's rebuttal Sunday.

At a news conference in Tokyo, Kerry stressed that gaining China's commitment to a denuclearized North Korea was no small matter given its historically strong military and economic ties to North Korea.

But he refused to say what the Chinese were offering to do concretely to pressure the North into abiding by some of the conditions it agreed to in a 2005 deal that required it to abandon its nuclear program.

"They have to take some actions," Kerry said of North Korea. "How many or how much? I'd have to talk to folks back in Washington about that. But if the Chinese came to us and said, 'Look, here's what we have cooking,' I'm not going to tell you I'm shutting the door today to something that's logical and might have a chance of success."

In remarks to U.S. journalists, Kerry said that under the right circumstances, he even would consider making a grand overture to North Korea's leader, such as an offer of direct talks with the U.S.

"We're prepared to reach out," he said. Diplomacy, he added, required risk-taking and secrecy such as when President Richard Nixon engaged China in the 1970s or U.S. back-channel talks were able to end the Cuban missile crisis a decade earlier.

Given their proximity and decades of hostility and distrust, Japan and South Korea have the most to fear from the North's unpredictable actions.

Kerry clarified a statement he made Saturday in Beijing, when he told reporters the U.S. could scale back its missile-defense posture in the region if North Korea goes nuclear-free.

It appeared to be a sweetener to coax tougher action from a Chinese government which has eyed the increased U.S. military presence in its backyard warily, but which has done little over the years to snuff out funding and support for North Korea's weapons of mass destruction program.

Kerry said America's basic force posture wasn't up to debate. "There is no discussion that I know of to change that," he said.

But he said it was logical that additional missile-defense elements, deployed specifically in response to the Korean threat, could be reversed if that threat no longer existed.

"I was simply making an observation about the rationale for that particular deployment, which is to protect the United States' interests that are directly threatened by North Korea," he said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-04-14-US-Japan-NKorea/id-c95f79d113d94a2f90c287880fcb61a4

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Sunday, April 14, 2013

Valet, Finder Codes, Ninja Jamms, and More

This week's collection of apps went all over the place in terms of content. If you're someone prone to bouts of amnesia during daily activities, there's plenty to cure what ails you down below. Aspiring musicians and video chat-junkies won't be disappointed either. Everyone else: maybe next week. More »
    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/p0KR7SUt6XE/valet-finder-codes-ninja-jamms-and-more

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Saturday, April 13, 2013

Blocking immune response protein helps body clear chronic infection; Potential therapy for HIV, other viral infections?

Apr. 11, 2013 ? UCLA scientists have shown that temporarily blocking a protein critical to immune response actually helps the body clear itself of chronic infection. Published in the April 12 edition of Science, the finding suggests new approaches to treating persistent viral infections like HIV and hepatitis C.

The research team studied type-1 interferons (IFN-1), proteins released by cells in response to disease-causing organisms that enable cells to talk to each other and orchestrate an immune response against infection. Constant IFN-1 signaling is also a trademark of chronic viral infection and disease progression, particularly in HIV.

"When cells confront viruses, they produce type-1 interferons, which trigger the immune system's protective defenses and sets off an alarm to notify surrounding cells," explained principal investigator David Brooks, assistant professor of microbiology, immunology and molecular genetics at UCLA's David Geffen School of Medicine and College of Letters and Sciences. "Type-1 interferon is like the guy in the watch tower yelling, 'red alert,' when the marauders try to raid the castle."

Scientists have long viewed IDF-1 as beneficial, because it stimulates antiviral immunity and helps control acute infection. Blocking IDF-1 activity, they reasoned, would allow infection to run rampant through the immune system.

On the other hand, prolonged IFN-1 signaling is linked to many chronic immune problems. The research team wondered whether obstructing the signaling pathway would enable the immune system to recover enough to fight off chronic infection.

To test this theory, Brooks and his colleagues injected mice suffering from chronic viral infection with an antibody that temporarily blocked IFN-1 activity.

Much to their surprise, they discovered that giving the immune system a holiday from IFN-1 boosted the body's ability to fight the virus. Stunningly, the respite also reversed many of the immune problems that result from chronic infection, such as a rise in proteins that suppress immune response, continuous activation of the immune system and disruption of lymph tissue.

The findings fly in the face of past studies that suggest eliminating IFN-1 activity in mice leads to severe, life-long infection.

"What we saw was entirely illogical," admitted Brooks. "We'd blocked something critical for infection control and expected the immune system to lose the fight against infection. Instead, the temporary break in IFN-1 signaling improved the immune system's ability to control infection. Our next task will be to figure out why and how to harness it for therapies to treat humans."

"We suspect that halting IFN-1 activity is like pushing the refresh button," said first author Elizabeth Wilson, a UCLA postdoctoral researcher. "It gives the immune system time to reprogram itself and control the infection."

Uncovering this mechanism could offer potential for new therapies to tackle viruses like HIV and hepatitis C, according to Brooks. The team's next step will be to pinpoint how to sustain IFN-1's control of the virus while blocking the negative impact that chronic IFN-1 activity wreaks on the immune system.

The National Institute of Allergy and Infectious Diseases and the UCLA Center for AIDS Research supported the research.

Brooks' coauthors included first author Elizabeth Wilson, Douglas Yamada, Heidi Elsaesser, Jonathan Herskovitz, Jane Deng and Genhong Cheng, all of UCLA; Bruce Aronow of the University of Cincinnati, and Christopher Karp of the University of Cincinnati and Bill and Melinda Gates Foundation.

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Story Source:

The above story is reprinted from materials provided by University of California, Los Angeles (UCLA), Health Sciences, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. E. B. Wilson, D. H. Yamada, H. Elsaesser, J. Herskovitz, J. Deng, G. Cheng, B. J. Aronow, C. L. Karp, D. G. Brooks. Blockade of Chronic Type I Interferon Signaling to Control Persistent LCMV Infection. Science, 2013; 340 (6129): 202 DOI: 10.1126/science.1235208

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/KziwAhoigYM/130411142712.htm

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Friday, April 12, 2013

Heat Goes on Retailers - industries - business | Stuff.co.nz

Retail spending is expected to rebound this month after Easter and warm weather took the wind out of March shopping.

Kiwis spent less on their credit and debit cards last month compared with February, in the first monthly spending slip in six months.

Spending in the core retail categories fell 0.8 per cent, or about $27 million, seasonally adjusted Statistics New Zealand data shows.

Clothing, footwear and soft goods shopping suffered the biggest blow - down 6.2 per cent, or $18m.

Total retail spending, including vehicle-related spending, fell 0.5 per cent last month, while total spending - which includes services and non-retail sectors such as health - was down 1.2 per cent, to $5.8 billion.

Westpac senior economist Michael Gordon said Easter wiped out two trading days in March - a rare event given Easter was usually in April - and that was likely to have affected the data.

A "strong rebound" was expected in April but "we'll need to take the two months' figures together to make sense of the trend".

- ? Fairfax NZ News

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Source: http://www.stuff.co.nz/business/industries/8534886/Heat-goes-on-retailers

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Sunday, February 3, 2013

School finance transparency bill advances | The Salt Lake Tribune

Education ? Measure would put more spending data online.

Lawmakers advanced a bill Friday that would allow Utahns to look up how much their schools spend online on specific programs, supplies and other expenses.

The Senate unanimously approved SB128 on second reading Friday, meaning it must be read one more time in the Senate before it moves to the House.

Bill sponsor Sen. Daniel Thatcher, R-West Valley City, said the bill wouldn?t ask schools or districts to collect any data beyond what they already do, but it would require them to share that data they already collect on the state?s transparency website. The bill would cost $15,800 mainly for changes to the website and training.

"Think about the kinds of policy decisions that can be discussed, that can be debated, with full transparency of financial expenditures," Thatcher said.

Several other lawmakers also spoke in support of the measure Friday, though earlier in the week some education leaders questioned the price tag and usefulness of such a change.

State Superintendent Martell Menlove said earlier this week that if the state were to put information online for every school in Utah, rather than just for school districts, he believes it would cost far more than $15,800. He also wondered about the value of such data to the public, given its complexity.


Copyright 2013 The Salt Lake Tribune. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

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Source: http://www.sltrib.com/sltrib/news/55750061-78/bill-data-transparency-friday.html.csp

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Inside a solar eruption: NASA's SDO provides first sightings of how a coronal mass ejection forms

Feb. 1, 2013 ? On July 18, 2012, a fairly small explosion of light burst off the lower right limb of the sun. Such flares often come with an associated eruption of solar material, known as a coronal mass ejection or CME -- but this one did not. Something interesting did happen, however. Magnetic field lines in this area of the sun's atmosphere, the corona, began to twist and kink, generating the hottest solar material -- a charged gas called plasma -- to trace out the newly-formed slinky shape. The plasma glowed brightly in extreme ultraviolet images from the Atmospheric Imaging Assembly (AIA) aboard NASA's Solar Dynamics Observatory (SDO) and scientists were able to watch for the first time the very formation of something they had long theorized was at the heart of many eruptive events on the sun: a flux rope.

Eight hours later, on July 19, the same region flared again. This time the flux rope's connection to the sun was severed, and the magnetic fields escaped into space, dragging billions of tons of solar material along for the ride -- a classic CME.

"Seeing this structure was amazing," says Angelos Vourlidas, a solar scientist at the Naval Research Laboratory in Washington, D.C. "It looks exactly like the cartoon sketches theorists have been drawing of flux ropes since the 1970s. It was a series of figure eights lined up to look like a giant slinky on the sun."

More than just gorgeous to see, such direct observation offers one case study on how this crucial kernel at the heart of a CME forms. Such flux ropes have been seen in images of CMEs as they fly away from the sun, but it's never been known -- indeed, has been strongly debated -- whether the flux rope formed before or in conjunction with a CME's launch. This case shows a clear-cut example of the flux rope forming ahead of time. Vourlidas is a co-author, along with Spiro Patsourakos and Guillermo Stenborg, of a paper on these results published in the Astrophysical Journal on Jan. 31, 2013.

Spotting such a foreshadowing of a CME could help scientists develop ways to predict them, says Dean Pesnell, the project scientist for SDO at NASA's Goddard Space Flight Center in Greenbelt, Md. "By telling us when and where flux ropes will erupt," Pesnell says. "SDO helps us predict a major source of space weather."

Scientific research is always a dance between hypothesis and experimental confirmation, and the history of the flux rope is no exception. Plasma physicists suggested that such coils of magnetic field lines were at the heart of flares in the 1970s and spacecraft near Earth provided in-situ measurements that occasionally traced out helical structures inside CMEs. Later, the flux ropes were spotted in images of CMEs captured by the joint ESA/NASA Solar Heliospheric Observatory (SOHO) -- which launched in 1995 -- using the mission's Large Angle and Spectrometric Coronagraph (LASCO), a telescope that blocks out the bright light of the solar disk in order to better see the tenuous corona around it. They are now a regular appearance on coronagraph and heliospheric imaging observations.

When it came to watching them form in a CME, however, the task was much harder. Since CMEs can form quite suddenly -- known as impulsive CMEs -- the associated flux ropes are smaller and closer to the surface, making it difficult to spot them amongst the many structures in the corona.

In the absence of direct observational evidence, theorists have produced two theories based on general physics of plasmas and magnetic fields of how and when the flux rope might form. In one, the magnetic structure of the rope exists before the CME, and as it evolves over time it twists and kinks becoming increasingly unstable. Eventually it erupts from the sun, releasing enormous amounts of energy and solar plasma. In the second version, the CME erupts when looping magnetic field lines are severed from the sun's surface. While the great blob of solar material streams off the sun, the fields reconnect with each other to form a classic flux rope shape.

"In this case, we saw this big eruption on July 19," says Vourlidas. "We wanted to analyze the eruption and we started going back in time -- a few minutes, then an hour, then eight hours. And then we saw it. A flux rope that looked just like the cartoons scientists have been drawing for decades."

Vourlidas credits this first sighting to three things. First, the team looked far enough back in time, when previous searches have often only looked a few minutes back. Second, the sun obliged its viewers with the perfect angle at which to see the tell-tale loops of the flux rope. SDO's cameras could look right down the center of the rope, like looking down the tunneled center of a slinky. Third, AIA's cameras capture imagery that no other cameras do: light at the 131 Angstrom wavelength, which shows solar material heated to temperatures of 10,000,000 K (18,000,000 F / 10,000,000 C). In images of the same region at the same time showing cooler material, the flux rope doesn't show up at all. AIA scientists chose to include a filter to view this unprecedentedly high temperature because they posited that flares could heat the corona to those temperatures. Apparently the same incredibly hot plasma helped highlight the flux rope that would later give rise to a CME.

Over the course of the next eight hours after the July 18 flux rope formed, the rope did show up faintly in images of cooler material, suggesting that the hot material from the flare cooled down over time as the flux rope also rose in space. Then eight hours later, on July 19, the material got hot again, the region flared, and the flux rope escaped into space.

"We could verify that the flux rope was there in the coronagraph from SOHO. We could see the typical slinky structure with multiple round loops inside it," says Vourlidas. "We looked at it with other NASA telescopes, too. We looked at it with everything we've got. It's a wonderful time to be a solar physicist, because thanks to the large number of telescopes we have in space at the moment, we can see things like this from every angle."

Vourlidas says that images from NASA's Solar Terrestrial Relations Observatory (STEREO) also helped with analysis. Since the two STEREO spacecraft observe the sun from a different perspective than does SDO, the team got a top-down view of the flux rope with STEREO-A's EUV Imager, which helped unravel the 3-D structure of the flux rope. The foot points of the rope touched in widely separated areas of the solar surface -- an interesting structural development in of itself that is worth further study.

The team will certainly look for other examples in the images of the hottest plasma, searching for evidence of pre-formed flux ropes further back in time. But even one such example of direct evidence adds an important step to the constant scientific cycle of theory and observation, helping refine and improve the theories of what causes these giant explosions on the sun.

For more information about NASA's SDO mission, visit: www.nasa.gov/sdo

For high resolution versions of this media, visit: http://svs.gsfc.nasa.gov/vis/a010000/a011100/a011180/

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The above story is reprinted from materials provided by NASA.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/space_time/nasa/~3/k7EPC4ymbr0/130201092746.htm

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